diff --git a/src/emu/debug/debugvw.c b/src/emu/debug/debugvw.c
index 89217b70447..4bf141c962a 100644
--- a/src/emu/debug/debugvw.c
+++ b/src/emu/debug/debugvw.c
@@ -2413,6 +2413,7 @@ static const memory_subview_item *memory_view_enumerate_subviews(running_machine
 					subview->next = NULL;
 					subview->index = curindex++;
 					subview->space = space;
+					subview->endianness = space->endianness;
 					subview->prefsize = space->dbits / 8;
 					strcpy(subview->name, astring_c(tempstring));
 					
@@ -2440,7 +2441,11 @@ static const memory_subview_item *memory_view_enumerate_subviews(running_machine
 		subview->index = curindex++;
 		subview->base = memory_region(machine, rgntag);
 		subview->length = memory_region_length(machine, rgntag);
-		subview->offsetxor = memory_region_length(machine, rgntag);
+#ifdef LSB_FIRST
+		subview->offsetxor = width - 1;
+#else
+		subview->offsetxor = 0;
+#endif
 		subview->endianness = little_endian ? ENDIANNESS_LITTLE : ENDIANNESS_BIG;
 		subview->prefsize = MIN(width, 8);
 		strcpy(subview->name, astring_c(tempstring));
@@ -2530,9 +2535,9 @@ static int memory_view_alloc(debug_view *view)
 	memdata->desc = view->machine->debugvw_data->memory_subviews;
 
 	/* start out with 16 bytes in a single column and ASCII displayed */
-	memdata->chunks_per_row = 16;
-	memdata->bytes_per_chunk = 1;
-	memdata->bytes_per_row = 16;
+	memdata->bytes_per_chunk = memdata->desc->prefsize;
+	memdata->chunks_per_row = 16 / memdata->desc->prefsize;
+	memdata->bytes_per_row = memdata->bytes_per_chunk * memdata->chunks_per_row;
 	memdata->ascii_view = TRUE;
 
 	return TRUE;
@@ -2888,6 +2893,9 @@ static int memory_view_needs_recompute(debug_view *view)
 	if (debug_view_expression_changed_value(view, &memdata->expression, (space != NULL) ? space->cpu : NULL))
 	{
 		recompute = TRUE;
+		view->topleft.y = (memdata->expression.result - memdata->byte_offset) / memdata->bytes_per_row;
+		view->topleft.y = MAX(view->topleft.y, 0);
+		view->topleft.y = MIN(view->topleft.y, view->total.y - 1);
 		memory_view_set_cursor_pos(view, memdata->expression.result, memdata->bytes_per_chunk * 8 - 4);
 	}
 
@@ -3261,16 +3269,20 @@ void memory_view_set_bytes_per_chunk(debug_view *view, UINT8 chunkbytes)
 
 	if (chunkbytes != memdata->bytes_per_chunk)
 	{
+		int endianness = memdata->desc->endianness;
 		offs_t address;
 		UINT8 shift;
 		
 		debug_view_begin_update(view);
 		memory_view_get_cursor_pos(view, &address, &shift);
+		address += (shift / 8) ^ ((endianness == ENDIANNESS_LITTLE) ? 0 : (memdata->bytes_per_chunk - 1));
+		shift %= 8;
+		
 		memdata->bytes_per_chunk = chunkbytes;
 		memdata->chunks_per_row = memdata->bytes_per_row / chunkbytes;
 		view->recompute = view->update_pending = TRUE;
-		address += shift / 8;
-		shift = (shift % 8) + 8 * (address % memdata->bytes_per_chunk);
+
+		shift += 8 * ((address % memdata->bytes_per_chunk) ^ ((endianness == ENDIANNESS_LITTLE) ? 0 : (memdata->bytes_per_chunk - 1)));
 		address -= address % memdata->bytes_per_chunk;
 		memory_view_set_cursor_pos(view, address, shift);
 		debug_view_end_update(view);
diff --git a/src/emu/mame.c b/src/emu/mame.c
index 8a8f41be2ac..be75dc31cff 100644
--- a/src/emu/mame.c
+++ b/src/emu/mame.c
@@ -761,22 +761,22 @@ int mame_is_paused(running_machine *machine)
 UINT8 *memory_region_alloc(running_machine *machine, const char *name, UINT32 length, UINT32 flags)
 {
 	mame_private *mame = machine->mame_data;
-	region_info *info;
+	region_info **infoptr, *info;
 
-    /* make sure we don't have a region of the same name */
-    for (info = mame->regions; info != NULL; info = info->next)
-    	if (astring_cmpc(info->name, name) == 0)
+    /* make sure we don't have a region of the same name; also find the end of the list */
+    for (infoptr = &mame->regions; *infoptr != NULL; infoptr = &(*infoptr)->next)
+    	if (astring_cmpc((*infoptr)->name, name) == 0)
     		fatalerror("memory_region_alloc called with duplicate region name \"%s\"\n", name);
 
 	/* allocate the region */
 	info = malloc_or_die(sizeof(*info) + length);
-	info->next = mame->regions;
+	info->next = NULL;
 	info->name = astring_dupc(name);
 	info->length = length;
 	info->flags = flags;
 
 	/* hook us into the list */
-	mame->regions = info;
+	*infoptr = info;
 	return info->base;
 }
 
@@ -795,14 +795,14 @@ void memory_region_free(running_machine *machine, const char *name)
 	for (infoptr = &mame->regions; *infoptr != NULL; infoptr = &(*infoptr)->next)
 		if (astring_cmpc((*infoptr)->name, name) == 0)
 		{
-			region_info *deleteme = *infoptr;
+			region_info *info = *infoptr;
 
 			/* remove us from the list */
-			*infoptr = deleteme->next;
+			*infoptr = info->next;
 
 			/* free the region */
-			astring_free(deleteme->name);
-			free(deleteme);
+			astring_free(info->name);
+			free(info);
 			break;
 		}
 }
@@ -1596,12 +1596,14 @@ static void init_machine(running_machine *machine)
 		(*machine->config->video_start)(machine);
 
 	/* free memory regions allocated with REGIONFLAG_DISPOSE (typically gfx roms) */
-	for (rgntag = memory_region_next(machine, NULL); rgntag != NULL; rgntag = nextrgntag)
-	{
-		nextrgntag = memory_region_next(machine, rgntag);
-		if (memory_region_flags(machine, rgntag) & ROMREGION_DISPOSE)
-			memory_region_free(machine, rgntag);
-	}
+	/* but not if the debugger is enabled (so we can look at the data) */
+	if (!options_get_bool(mame_options(), OPTION_DEBUG))
+		for (rgntag = memory_region_next(machine, NULL); rgntag != NULL; rgntag = nextrgntag)
+		{
+			nextrgntag = memory_region_next(machine, rgntag);
+			if (memory_region_flags(machine, rgntag) & ROMREGION_DISPOSE)
+				memory_region_free(machine, rgntag);
+		}
 
 	/* initialize miscellaneous systems */
 	saveload_init(machine);
diff --git a/src/emu/memory.c b/src/emu/memory.c
index 299bd292aaf..e3bbc7f23e4 100644
--- a/src/emu/memory.c
+++ b/src/emu/memory.c
@@ -3775,8 +3775,8 @@ UINT64 memory_read_qword_masked_8le(const address_space *space, offs_t address,
 
 UINT64 memory_read_qword_8be(const address_space *space, offs_t address)
 {
-	UINT64 result = (UINT64)memory_read_dword_8le(space, address + 0) << 32;
-	return result | ((UINT64)memory_read_dword_8le(space, address + 4) << 0);
+	UINT64 result = (UINT64)memory_read_dword_8be(space, address + 0) << 32;
+	return result | ((UINT64)memory_read_dword_8be(space, address + 4) << 0);
 }
 
 UINT64 memory_read_qword_masked_8be(const address_space *space, offs_t address, UINT64 mask)
@@ -3957,8 +3957,8 @@ UINT64 memory_read_qword_masked_16le(const address_space *space, offs_t address,
 
 UINT64 memory_read_qword_16be(const address_space *space, offs_t address)
 {
-	UINT64 result = (UINT64)memory_read_dword_16le(space, address + 0) << 32;
-	return result | ((UINT64)memory_read_dword_16le(space, address + 4) << 0);
+	UINT64 result = (UINT64)memory_read_dword_16be(space, address + 0) << 32;
+	return result | ((UINT64)memory_read_dword_16be(space, address + 4) << 0);
 }
 
 UINT64 memory_read_qword_masked_16be(const address_space *space, offs_t address, UINT64 mask)
@@ -4133,8 +4133,8 @@ UINT64 memory_read_qword_masked_32le(const address_space *space, offs_t address,
 
 UINT64 memory_read_qword_32be(const address_space *space, offs_t address)
 {
-	UINT64 result = (UINT64)memory_read_dword_32le(space, address + 0) << 32;
-	return result | ((UINT64)memory_read_dword_32le(space, address + 4) << 0);
+	UINT64 result = (UINT64)memory_read_dword_32be(space, address + 0) << 32;
+	return result | ((UINT64)memory_read_dword_32be(space, address + 4) << 0);
 }
 
 UINT64 memory_read_qword_masked_32be(const address_space *space, offs_t address, UINT64 mask)
diff --git a/src/osd/windows/debugwin.c b/src/osd/windows/debugwin.c
index febf33776cb..a09cb1740ed 100644
--- a/src/osd/windows/debugwin.c
+++ b/src/osd/windows/debugwin.c
@@ -1683,7 +1683,7 @@ static void memory_create_window(running_machine *machine)
 	const memory_subview_item *subview;
 	debugwin_info *info;
 	HMENU optionsmenu;
-	int cursel = 0;
+	int cursel = -1;
 
 	// create the window
 	info = debugwin_window_create(machine, "Memory", NULL);
@@ -1738,9 +1738,10 @@ static void memory_create_window(running_machine *machine)
 		TCHAR *t_name = tstring_from_utf8(subview->name);
 		int item = SendMessage(info->otherwnd[0], CB_ADDSTRING, 0, (LPARAM)t_name);
 		free(t_name);
-		if (cursel == 0 && subview->space != NULL && subview->space->cpu == curcpu)
+		if (cursel == -1 && subview->space != NULL && subview->space->cpu == curcpu)
 			cursel = item;
 	}
+	if (cursel == -1) cursel = 0;
 	SendMessage(info->otherwnd[0], CB_SETCURSEL, cursel, 0);
 	memory_view_set_subview(info->view[0].view, cursel);